It's definitely possible to target a certain surface location on the moon from low Earth orbit and set off on a trajectory to get there with a single burn. However, as the craft(s) approach the moon and enter its sphere of influence, gravity will kick in and increase their relative velocity to the surface. Another burn (suicide burn if you're feeling lucky) would be needed for the soft touchdown.
The moon is also gravitationally very "lumpy", so some small corrections might be needed along the way as well.
First time encountering the phrase “gravitationally lumpy”. I can imagine what that is. But why? I suppose it would naturally occur if the moon were not more or less consistent density. But how would that be possible given the moon’s age and shape. (Roughly spherical I am assuming)
Buried "mascons" (mass concentrations), https://en.wikipedia.org/wiki/Gravitation_of_the_Moon has some nice color maps of the deviations/anomalies. (TLDR: some of it is explained by basalt but not all of it, and it's still being studied, because it interferes with low altitude lunar orbits.)
Space applications of all sorts are screaming out for mass production approaches. With so much design work and verification the actual manufacturing cost tends to be trivial by comparison, the work readily adapted to concurrent manufacturing processes.
When I signed on to a Mars mission in 1999, the scientists told me that’s JPL’s approach: instead of extremely expensive, robust, redundant craft, they would begin to make leaner stuff and worry less when it failed...
Around the same time, Mission Control was replacing their bespoke hardware with COTS and trying to minimize the “glue” HW/SW for space systems.
You'll also see that expertise on a particular instrument package is leveraged over and over across multiple missions.
NASA still has amazing educational outreach and makes incredible software, even for mere mortals.
Combine that with leaving the long-range comms (and higher-powered equipment) in lunar orbit as the "master" for all the probes scattered on the surface, and maybe the problem becomes simpler by breaking it in two.
Instead of building all these expensive to launch big landers, why not get some pizza-box sized probes into earth orbit AND THEN do like a slo-mo golf shot arcing to where the moon will be for a super slow/soft landing?
Some will fail but if you launch 100 and get 20-30 working, there you go.
As technology progresses, get it down to a shoe-box sized probe and then in 10 years smartphone sized (in 100 years tic-tac sized).