Full reusability would totally change the game. It'd be an order-of-magnitude cost reduction. Maybe even 2 orders of magnitude (cost per kg to orbit)
Full reuse can be anywhere from more expensive to multiple orders of magnitude cheaper, thus could rather than would.
Questions like rate of successful launches, amount of payload sacrificed, etc really change the economics of the whole process. If the total payload is worth 1 billion a moderately more expense launch with higher success rate can be cheaper.
Going fully reusable may change that equation, but first stage reuse probably isn’t enough to make the program even close to worthwhile.