We’ve had all three in NYC (depending on what you mean by antifa since outside of Seattle it’s mostly a non-existant scarecrow of right wing talking heads) and things are booming. Homelessness is pretty bad and crime has climbed, but we’re very far from the 80’s and 90’s, and the city is very alive with restaurants thriving.
That said the changes due to work from home are far more devastating than anything else to specific Manhattan neighborhoods that relied on large workday populations that have yet to return, so I wouldn’t say it’s all roses.
Seattle continues to be dead just about every night of the week, compared to the before times. Head north 15 miles to Lynnwood in the next county over however, and things have continued to remain really vibrant and busy. I'm talking about the difference of a restaurant having a few tables seated, vs being full and having to wait.
Several differences in policy stand out to me: vax passes, antifa, and the homeless.