- There were reports that if you inject the goo from melting the tumor into another mouse, that mouse became much more resistant to that class of tumor[1], so...
[1] - https://news.engin.umich.edu/2023/10/these-bubbles-kill-canc...
- This makes sense to me.
Having spent a bunch of time with people who have had persistent issues with stable income, a lot of them internalize it at various levels as them personally not being worth anything, because so many systems involved seem to be operating in bad faith.
Anything involving the US medical system, for instance - even as someone working in tech with good health insurance, so many of my interactions with doctors can be summarized as "the doctor makes a snap judgment in the first 30 seconds of interacting with you, and arguing with it results in them interacting in bad faith thereafter".
And that's not as bad as other machinery in the US. The advice I've heard around trying to use the limited social safety machinery in the US is "plan for it to be a fulltime job for multiple years to get on it, and expect to randomly be kicked off it repeatedly".
And having the systems you interact with regularly very clearly act in bad faith, assuming by default you don't deserve things, does things to people's mental health.
- It's not a negative, at all.
I just shared it because it's sort of like learning Slack started life as the internal communication tooling for the online game glitch, or that a lot of the "weird Twitter" folks started life as FYAD posters - once you know that, you can draw the lines between the two points.
- Oh, it's not bad or janky (...okay, no, it was in some ways janky, but on purpose), I loved that game.
But the sense of humor/tone between the two games is very visibly the same thing.
- A lot of things suddenly made sense when I learned their prior work was Magicka.
- Seeing neurons fire in recognizing the homage in the site appearance that haven't fired in 20 years was wild. Thanks for that.
- I would be surprised if they moved to ARM any time soon, because even if the CPUs can punch that hard, they're definitely not competing on the GPU front, from what I understand of the state of the art outside of Apple, so they're gonna wind up with a dGPU anyway if they did.
Maybe my knowledge is out of date, but I'd be kind of surprised if a Snapdragon can get anywhere near competing with even the existing Steam Deck on GPU performance. Looking at [1] for a ballpark number on Snapdragon GPU performance doesn't seem encouraging.
[1] - https://chipsandcheese.com/p/the-snapdragon-x-elites-adreno-...
- I would assume Steam Deck 2 isn't dropping before at least H2 2026, if not later, if they didn't bring it out with the announcement of the other devices.
- I've been really curious precisely what changed, and what sort of optimization might have been involved here.
Because offhand, I know you could do things like cute optimizations of redundant data to minimize seek time on optical media, but with HDDs, you get no promises about layout to optimize around...
The only thing I can think of is if it was literally something as inane as checking the "store deduplicated by hash" option in the build, on a tree with copies of assets scattered everywhere, and it was just nobody had ever checked if the fear around the option was based on outcomes.
(I know they said in the original blog post that it was based around fears of client performance impact, but the whole reason I'm staring at that is that if it's just a deduplication table at storage time, the client shouldn't...care? It's not writing to the game data archives, it's just looking stuff up either way...)
- This is only true in places where there are more people trying to rent than places.
In theory, having more capital available in the face of a landlord raising rent an obnoxious amount will incentivize people who aren't making much to move somewhere with a lower CoL that they might not have been able to make work otherwise because of uncertainty in the amount of time they'd be out of work or their base level of money available for that time.
- In a number of cases, yes.
I'm not remarking that the premise is entirely without merit, just that there's some emergent cases where it actively made things worse.
- Once upon a time, someone at Microsoft wished on a monkey's paw for a way to replace thousands of undocumented INI files throughout the filesystem.
It curled, and we got the registry.
- The problem with that is, in places where delivery is ubiquitous, people use the reusable bags the same as they used the single-use bags, and there's no way to return them, so now people are disposing of much more resource-intensive bags the same way they did the single-use ones.
- I don't think they want to kill it entirely in the next 5 years, at least, but I do think they just want to stop supporting the non-enterprise users because that lets them significantly constrain what hardware and features they have to maintain, and all their big software offerings are very content being sold as cloud-based recurring revenue sources.
I would assume after 11 LTSC finally EOLs might be the earliest they'd be considering anything more drastic, but I wouldn't speculate whether it'd look like a good idea by then.
It may sound wild, and certainly possible time will prove me wrong, I'm not an oracle, but the ongoing failures in basic functions in Windows seems like they're removing significant investment in it as a reliable platform for general use going forward, and their recent introduction of things like the Xbox handheld running Windows makes me suspect their goal is to constrain where it's still used, and trim how much it costs to maintain that way.
- I would assume because it's hideously expensive to maintain a full OS and support and compatibility guarantees with all the random horseshit consumer platforms throw at them, and they did the math and concluded they liked the profit margins for purely online and non-consumer targeted things, where they can more effectively constrain what is and isn't supported, better.
In particular, my guess is that they looked at their estimates for how much they could make off recurring revenue sources in desktop OSes, and their estimates for how the desktop market is changing with more younger users not using them or viewing them as legacy platforms, and decided they should pivot to primarily being a services provider, in much the same way they're aggressively trying to slap the Xbox branding on other things and getting out of the console market as fast as they can run.
Could be wrong, I don't work there, but usually my experience with companies that large making apparent missteps is that their goal isn't the one you think it is, and attempting to extract as much data as they can from desktop users really sounds like what you do when you're trying to squeeze the sponge before you throw it out.
- I do still strongly suspect Microsoft's endgame is to get people off Windows in the consumer space, and that most of what's going on right now with 11 is froth as they add features they think will make them money in the near term even as it drives people off or be useful in the non-consumer space, not because they sincerely think this is something people will find a net gain in the consumer space.
So yes, I agree it's likely not primarily ignorance driving this.
- The largest problem with dealing with humans is handling both good and bad faith cases.
In particular, if you can't rely on the escalation path being willing to rule a lawsuit is "bloody stupid" if you offer, say, a discount on "all fruits" and someone tries to argue milk is a fruit, then you wind up with endless escalations of rules lawyering and perverse effects.
- 11, I think, is what happened when they wanted to push breaking changes that customers who pay for LTSC wanted to avoid for the entire lifetime of 10.
My assumption is that 10 was as you describe, and then 11 was motivated by wanting to make disruptive changes to squeeze the last juice from the consumer segment, and the "agentic OS" pivot is just the most recent gorilla in the room to squeeze the ever-drier sponge.
In particular, I would assume Microsoft sees writing on the wall with how so many people in younger demographics are using phones as primary devices and see full sized laptops and desktops as effectively legacy platforms they use at jobs, and is frantically trying to get out of that market before the bottom falls out.
- The nuance there, I think, is that over half the players are reportedly new to the Diablo games, which suggests that their primary intended market was likely not existing Diablo players.
The core kernel of it always seemed, to me, to be an extension of the Diablo 3 RMT auction house idea - they wanted a recurring revenue source from a franchise where traditionally they were not charging one, and in this case, they squared that circle by appealing to users who were not existing players, and so did not have those norms in mind.
The key thing is, one of the things most tumors need to do to get past a certain point is avoid getting caught being tumors.
If you can very selectively cause precise tissue death, from any method, then your body will suddenly start looking askance at any tissue that looks like the secretly-full-of-tumor-markers corpse it just found.
And ultrasonic cavitation means you can, in theory, cause very precise tissue death with even less surrounding effect than radiation.