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dbcooper
Joined 4,489 karma

  1. A key limiting factor for dietary use of single cell protein is the high mass fraction of nucleic acid, which limits daily consumption due to uric acid production during metabolism. High rates of RNA synthesis are unfortunately necessary for high protein productivity.

    The paper notes:

    >It is important to note that MP products often contain elevated levels of nucleic acids, constituting ~8% of the dry weight [17], which necessitates consideration when assessing their suitability for human consumption. To address this, a heat treatment process is employed at the end of fermentation that reduces the nucleic acid content in the fermented biomass to below 0.75/100 g, while simultaneously deactivating protease activity and F. venenatum biomass. However, this procedure has been observed to induce cell membrane leakage and a substantial loss of biomass, as evidenced in the Quorn production process [17], which also utilizes F. venenatum as the MP producer. Our experimental trials have encountered similar challenges, achieving a biomass yield of merely ~35%, and observed that heating process increased the relative protein and chitin content (Figure 2D,E), which may be related to the effect of membrane leakage, while the intracellular protein of the FCPD engineered strain was less likely to be lost to the extracellular. Thus, concentrating the fermentation broth to enhance protein and amino acids content in successive steps to produce a highly nutritious water-soluble fertilizer appears to be an effective strategy for adding value to the process (Figure 1).

    The challenges of developing economic single cell protein products, that are suitable for human consumption, are described in chapter 3 here:

    https://www.researchgate.net/profile/Martin-Hofrichter-2/pub...

  2. wushowhide.diagcab
  3. There's a tool for blocking selected driver updates that still works on Windows 11. Very handy.
  4. Nick Mullen should be the guest of honor at this event.
  5. What chemistry would they use for the photoresist type resins?
  6. Can't even read the abstract without paying. That's a new low.
  7. Yep. Enable extensions in edge://flags/. Then you can use ublock origin. You can install any crx file extension if you enable developer mode.
  8. I'm running it on a device with a Qualcomm SM8635 Snapdragon 8s Gen 3 chipset, and it just crawls. The UI is very unresponsive, and page load times are terrible.

    For youtube background play Brave is much better.

  9. Firefox for Android is some of the worst software I've ever used. A lot of extensions won't work in it, and even Edge Canary is far better with them. It is extremely slow, and the UI is horrible.

    I'm running it on a device with a Qualcomm SM8635 Snapdragon 8s Gen 3 chipset, and it just crawls. The UI is very unresponsive, and page load times are terrible. It also has to reload the page if it was running in the background and you switch back to it.

  10. Does this work for videos flagged as age-restricted, or paid subscriber content? IIRC, yt-dlp needs to be passed browser cookies to do so?
  11. You can use nextdns for DNS adblocking.
  12. Anyone have a spare invite?
  13. Cosmic Text (Cosmic DE) might do this on the GPU via swash. It has subpixel rendering.
  14. >Why you should trust me

    Absolutely zero mention of qualifications. If you do not have a chemistry/chemical engineering degree, or something closely related then why would anyone want to bother with your verbose writing?

  15. The "infrastructure" is terrible software called Editorial Manager. It doesn't have any document annotation or collaboration features. It merely allows documents to be uploaded and downloaded, and is a pain to work with.

    The peer review process is almost entirely coordinated by unpaid associate editors. They make initial manuscript assessments, solicit reviewers, and moderate the review and response process.

    "journal staff moving papers through the peer review system" may happen at a small number of prestige journals such as Advanced Materials, but for most Q1 journals it is all volunteer work. That is the business model that makes companies like Elsevier billions.

  16. Peer review is not supported by publishers. Many editors are unpaid too.

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