- Principles of Vitrification (Fahy PDF linked) p. 48 many practitioners think they have vitrified when they have not p. 45 volume changes of vitrifying agents, possibly in a way that avoids detection (very small scale?).
Covers the second term, "freezing" (quibble quibble) speed and delays in the procedure cover the first.
Your team seems not to be trying to maintain either normally solid/fluid tissue maintaining recoverable gradients or vitrification through an entire cycle below the triple point (with just removable or bio-compatible vitrifying mixtures) so your "goal" might be easier. Is the future AI just going to say you didn't do well enough even if you meet your "goal"?
On the other hand if there's never any point in the cycle where any volume is not either recoverable to health or vitrified, all the AI can say is that cryonics doesn't work period.
- This is optimistic, I see "The cryonics people make a mistake in freezing you (how do we know they don't make lots of mistakes?)"[0] and "The current cryonics process is insufficient to preserve everything"[0] resulting of a product 10% already, seemingly matching the questionnaire as well as possible. They say "under ideal conditions" in the survey, so maybe that rules out cracking of brain tissue or ice growth, but that's not the number practitioners want to know about.
[0]: https://www.jefftk.com/p/breaking-down-cryonics-probabilitie... “Principles of Cryopreservation by Vitrification” https://gwern.net/doc/biology/2015-fahy.pdf
- https://en.wikipedia.org/wiki/Nolo_contendere There you still have booleans, just two of them instead of one.
- Did an LLM convince you to put in the anthropic argument entry in the galaxy brained section? Claude Opus?
- There's nothing on here, not even pre-registration of studies, let alone what J. D. Vance brought up about the replication crisis.
- > the optimum is a bit thicker than our guidance suggests
That's probably confounded. Anything over a BMI of 23 better be an increasing proportion of muscle, and even then there's a point that the stress on the heart isn't worth it.
Almost every physical and mental heath condition does bad things to nutrition and internal energy stores, even if only at a diet level.
It's hard to see since so many people are overweight or obese to start with, but the overall correlation goes that way enough to cause confounding.
- Not very good. The writing is okay, but walking away isn't better than deluding yourself with justification. Yes I get it's all metaphor, but that doesn't make it better.
If you actually read the thing, within the literal story it never says there's actually anywhere better, or any better place could exist.
- I don't see how that could provide an alternative to Novikov fixpoints. You can't control the initial conditions well enough, so the Novikov fixpoint you get is one where no observable time travel has ever occurred.
I think you're getting too attached to fixpoints and worldlines, it would be better to think through the actual computer program the simulation uses.
- Does it matter? If the system does something, the system does something.
The thing was huge. They were training the thing to be GPT5, before they figured out their userbase to too large to be served something that big.