- 3eb7988a1663I heard an argument that the fake jobs are actually to appease internal employees. "We know you are over-worked, but we are trying to get you some help. Look at these postings -too bad everyone who has applied thus far is a complete dud."
- The link to your community built missions is down.
- Ultimately most of these decisions come down to economics and not mustache twirling villains. The banality of evil.
Simplest "bad" reasons are the wealth of the patients. Malaria, river blindness, guinea worm, etc are terrible diseases that mostly impact poor people out of sight from Western eyes. Spending $X billion developing a drug for a population that can barely afford to feed themselves is not going to make a financial return on investment.
- Misery loves company. I am certainly intrigued to see what is out there.
- Never looked into this. I would expect the majority of images would fail in this configuration. Or am I unduly pessimistic?
- I am also really curious how GP was able to pinpoint the event. Or was it more, "Well this is the one weird thing I did on my machine this week."
- Prevalence of the disease - if it only impacts 1/100 million, going to be hard to ever find sufficient patient population to test and recoup your investment.
Existing quality of treatments - if there are already efficacious drugs on the market - how sure are you that this new therapy will be best in class? Only being as good as the status quo is not an ideal competitive position. Conversely, if there is an unmet need because a disease is so lethal/debilitating, regulatory agencies can give latitude in approvals.
Likelihood patient compliance - if it is the most effective drug in the world, but requires intravenous infusion six times a day - nobody is going to adhere to that. GLP drugs are effective, but there is a needle-phobia that is preventing patients getting on board with the idea. Which is why there is an arms race for the first company to develop an oral version.
Toxicity - all chemicals are poisonous. Yet some have a lower therapeutic window than others. If you drug does what it should, but if you take 2x as much and it gives you a heart arrhythmia that is going to be a tough approval for anything but the most deadly conditions.
- This Kafka nightmare is somewhat funny when it does not impact your life, but with increasing centralization, I worry for the future. What happens when an AppleID/Google account in good standing is required to open a bank account? Go grocery shopping? Hold your drivers license? Apply for a job anywhere?
Big tech has repeatedly shown that they are willing to ignore life destroying account workflows so long as they only impact a minority.
- I thought there were many first and third party services looking for this kind of thing (AWS, Github, GWS, crypto, etc tokens). Seems weird that a F500 company repo was not receiving the regular, let alone extra deep scanning which could have trivially found these.
There was a recent post from someone who made the realization that most of these scanning services only investigate the main branch. Extra gold in them hills if you also consider development branches.
- There is also CodingFont if you want to do a tournament selection to find your preference.
- Not only must the il1 O0 series be distinguishable, but they need to stand on their own. If I only see one in isolation, can I know if that it must be a capital O and not a zero?
- Are they taking requests? I know just enough CSS to hang myself, but one thing I can never keep straight in flexbox is "align" vs "justify". Could not have used something like "main-axis" or "cross-axis"? Intentionally had to be somewhat obtuse from how it would be used?
- I recall "inventing" bubble sort during one of my first CS classes when the question was posed of how to sort a list. So, not that outlandish.
- If the code gets released, is it plausible I could patch my TV? Or would the loading process be esoteric/signed bootloaders/whatever impediments that I could not functionally do anything with it?
- For a while with bitcoin, it seemed GPU investing was almost a thing.
I just checked, the kit I bought in February was $270, today it is showing up for $1070. Woof. Now I have to decide if I should keep it on the off chance I do get around to that machine or dump it while the getting is good. Then again, who wants to buy RAM of unknown provenance unless they themselves are looking to scam the seller.
- Holy cow. I have 96GB of DDR5 I bought at start of year for a machine which never materialized. Might have to flip it.
That deep focus time that comes from being in an open office environment.Employees are encouraged to decline meetings that interfere with focus time.- I already get annoyed at police helicopters hovering at night. I can only imagine what dozens of different delivery services would sound like.
- TIL. I have always wondered how much pain you have to bear if you lose your ID on a (domestic) trip. Thought it was legitimately possible you might have to take a bus cross country.
- Pandoc has had "smart" typography[0] which generates em-dash and en-dash for a long time. I found a forum post for 2011 where people were discussing em dashes and such. That thread indicates that John Gruber created a Markdown extension in 2004 which was already handling en and em dashes[2].
[0] https://pandoc.org/demo/example33/7.1-typography.html
[1] https://pandoc-discuss.narkive.com/PHmQaAgM/en-dashes-vs-em-...