The gains from MoE is that you can have a large model that's efficient, it lets you decouple #params and computation cost. I don't see how anthropomorphizing MoE <-> brain affords insight deeper than 'less activity means less energy used'. These are totally different systems, IMO this shallow comparison muddies the water and does a disservice to each field of study. There's been loads of research showing there's redundancy in MoE models, ie cerebras has a paper[1] where they selectively prune half the experts with minimal loss across domains -- I'm not sure you could disable half the brain and notice a stupefying difference.

[1] https://www.cerebras.ai/blog/reap