Do you sell vms or something? It's absurd to even consider running an entire os in a vm just to use the calculator or the notepad.
The only time it's worthwhile is when you pay thousands of dollars for a license, and don't want to spend on an annual maintenance contract. For example, I've got a ~10 year old IDA Pro license server in an Ubuntu 16.04 VM.
QubesOS would like a word with you. https://www.qubes-os.org/
Why not? VMs can be given access to the host file systems.