The 50 move rule is still there: either player has the right to claim a draw after 50 moves without a pawn move or a capture. So the game can end then if either player wishes it to (and it almost always will end, because at least one player can expect no better than a draw).
After 75 moves, however, it's not optional, the game has ended. It's still a draw if the game subsequently "ends" in checkmate or a loss on time, though maybe not the players sign the score sheet, move on to the next round, etc.
After 75 moves, however, it's not optional, the game has ended. It's still a draw if the game subsequently "ends" in checkmate or a loss on time, though maybe not the players sign the score sheet, move on to the next round, etc.