> Do those larger alcohol compounds have known downsides similar to ethanol (e.g. carcinogenicity)?
From a cursory search, yes. It is more toxic than ethanol, even in gross terms like LD50.
https://pubchem.ncbi.nlm.nih.gov/compound/isoamylol#section=...
Longer alcohols also contribute a lot to hangovers.
Nice, so we can have a beer that doesn't get us drunk, but does give a hangover?
A puritian dream. Pay, sinner, pay for your hedonistic pleasures!
> A puritian dream. Pay, sinner, pay for your hedonistic pleasures!
I am not aware of such uses for alcohol, but for hallocinogenic drugs, there exist people who don't use them for hedonistic pleasures, but for getting creative, scientific or spiritual inspirations.
Most mainstream Japanese lager is made partially from rice (in these lagers, over 1/3rd of the grain used is rice), so the flavor difference is probably already familiar to many people.