Nah, not much changed in the past 40-50 years; between the two, Lisp and Smalltalk spearheaded pretty much all the stuff that was added to other programming languages in subsequent decades, and some of the things yet to be added.
The main thing that changed about programming is the social/political/bureaucratic side.
"broadly" does a lot of work in his statement. But as an old dude who has done these things, it isn't deeply different.
I love Andrej, but come on.
Writing essentially punch cards 70 years ago, writing C 40 years ago and writing Go or Typescript or Haskell 10 years ago, these are all very different activities.