It's worth highlighting that first result is exactly what you asked for, given all 4 of your criteria:
1. It's on adults.
2. It's longitudinal over multiple years.
3. It studies variations in brain volume.
4. It focuses on healthy individuals.
You can see the full results for that search text here: https://undermind.ai/query_app/display_one_search/e1a3805d35...
And that first hit in JAMA Open is a fabulous paper. Ten or mire yearly MRI scans for 650 subjects.
Claude 3.5 is reluctant to provide references—-although it will if coaxed by prompting.
Undermind solves this particular problem. A great complement for my research question —- the evidence that brain volume is reduced as a function of age in healthy cognitively normal humans. In mice we see a steady slow increase that averages out to a gain of 5% between the human equivalents of 20 to 65 years of age. This increase is almost linear as a function of log of age.
Here is the question that was refined with Undermind’s help:
>I want to find studies on adult humans (ages 20-100+) that have used true longitudinal repeated measures designs to study variations in brain volume over several years, focusing on individuals who are relatively healthy and cognitively functional.
I received 100 ranked and lightly annotated set of 100 citations in this format:
>[1] Characterization of Brain Volume Changes in Aging Individuals With Normal Cognition Using Serial Magnetic Resonance Imaging S. Fujita, ..., and O. Abe JAMA Network Open 2023 - 21 citations - Show abstract - Cite - PDF 99.6% topic match Provides longitudinal data on brain volume changes in aging individuals with normal cognition. Analyzes annual MRI data from 653 adults over 10 years to observe brain volume trajectories. Excludes populations with neurodegenerative diseases; employs true longitudinal design with robust MRI techniques.