I assume no based on your comment, but have you ever run into issues where your vfio setup didn’t work with AAA games with intense anti cheat? Like cs:go/cs2 or valorant? That’s what’s always held me back
Not all, but many, of these can be avoided with edits to the libvirt XML. Some things just rely on seeing hyper-v extensions. Others use more indicators.
Since you mention CS - I had ESEA working and they're notably difficult to bypass. Valorant was the only game I couldn't figure out that I had tried. Destiny was fine.
Past tense because I've chosen liberty instead - not playing anything with invasive AC, dropping Windows, and running Linux full time
I haven't so far. CS:GO and now CS2 run natively on Linux, so never played those online in the VM. I hear Valorant's anticheat is trouble, but I haven't played it (and probably won't for that reason; personally I have so many other games left to play I'd probably just do that instead of having to install Windows on a separate boot drive).
VM running using libvirt and virt-manager, using QEMU underneath, with custom hook script that makes passing through the hardware a bit more seamless.
Although with how awesome Wine/Proton and ecosystem are these days I have so far played almost all my games on Linux. I created the VM setup because I thought I'd need it, but turns out I didn't really. Think I've played through 20-30 games or something like that now with minimal issues on Linux, including big budget AAA games within a few days of their release, smaller indie games, all kinds of different ones. Most tinkering required was for older games that'd need similar tweaks on modern Windows as well.